TiO₂-Free Capsules
What Are TiO₂-Free Capsules?
TiO₂-free capsules are empty hard shells formulated without titanium dioxide. They emerged in response to the European Union’s ban on titanium dioxide as a food and supplement additive.
To replace titanium dioxide, the traditional whitening and opacifying agent in empty capsule manufacturing, alternatives like calcium carbonates, zinc oxides, and iron oxides are increasingly used in shell formulations.
TiO₂-free technology is available across all major capsule types, including gelatin, HPMC, and pullulan capsules.
Even though titanium dioxide remains permitted in certain markets, many global brands have transitioned to TiO₂-free capsules to use a single formula for worldwide distribution.
Why Choose Anxine’s TiO₂-Free Capsules
EU Compliance Support
Formulated without titanium dioxide for products intended for restricted markets.
Clean-Label Verification
Removes controversial synthetic whiteners to support strict chemical-free marketing claims.
Uncompromised Opacity
Mineral alternatives deliver efficient ingredient masking and a uniform capsule appearance.
Changeover-Free Machinability
Immediate 1:1 replacement with standard capsules on automated capsule filling lines.
Certifications
Verifiable manufacturing standards. Essential support for TiO₂-free product compliance and market access.
TiO₂-Free Capsule Size Chart
Available in commonly used capsule sizes for a wide range of formulations while maintaining TiO₂-free compliance.
Regulatory Applications & Adoption Considerations
TiO₂-free capsules work well with most standard formulations. But they may not always be the right choice for your product.
✔ Recommended Applications
- EU-bound products: Suitable for dietary supplements and nutraceuticals intended for sale in regions where titanium dioxide is restricted.
- Global compliance: A practical option to meet ingredient regulations in different countries. You only need to replace the titanium dioxide-containing capsule shells without reformulating the contents.
- Clean-label formulations: Use natural minerals to achieve comparable opacity and color. Particularly suitable for HPMC and pullulan capsule products emphasizing clean-label or vegan claims.
⚠️ Practical Limitations
- Light-sensitive formulations: Calcium carbonate opacifiers provide lower light protection than titanium dioxide. For highly light-sensitive products, additional iron oxides may be required.
- Capsule appearance: TiO₂-free shells may appear less bright or less opaque than traditional titanium dioxide capsules.
- Regional requirements: Alternative opacifiers should still be reviewed against local regulations. For example, the permitted usage limits of iron oxide systems vary across regions.
FAQs About TiO₂-Free Capsules
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We Offer
Explore cutting-edge pharmaceutical and packaging machinery with Anxine. Supported by expert custom solutions and a robust global service network.
Capsule Filling Machine
Capsule filler machines are used to efficiently fill empty capsules with precise amounts of powders, granules, pellets or liquid in pharmaceutical and supplement production.
Tablet Press Machine
Tablet press machine is a specialized machine for producing tablets and pills.
Softgel Encapsulation Machine
A softgel encapsulation machine is designed to fill and seal liquid or semi-liquid materials into soft gelatin capsules.
Gummy Making Machine
Gummies making machines are automated systems used to produce gummy candies and supplements for the confectionery and pharmaceutical industries.
Industrial Powder Blender
Powder blenders achieve fast, uniform mixing of materials across batches and are widely used in the pharmaceutical, food, and chemical industries.
Pill Counting Machine
Engineered to rapidly and accurately count tablets, capsules, and gummies. Automate your pharmaceutical packaging process with diverse solid dosage counting solutions.
Blister Packaging Machine
Engineered for pharmaceutical and nutraceutical production, this equipment reliably forms and seals Alu-PVC and Alu-Alu packs for tablets, capsules, and softgels.
Cartoning Machine
Creates an extra protective layer for your product and makes shipping easier. Accurately inserts bottles, blister packs, pouches, and tubes into boxes for pharmaceutical, cosmetic, and food packaging.
Pouch Packing Machine
Automated pouch filling and sealing systems. Precisely dose powders, granules, liquids, and solids to streamline your pharmaceutical, nutraceutical, and food packaging lines.
Liquid Filling Machine
Precision equipment engineered to accurately dispense liquids, pastes, creams, and gels for efficient pharmaceutical, cosmetic, and chemical production lines.
Empty Capsules
We provide a variety of capsule shells in different sizes and materials for diverse formulations and target groups. They are suitable for the pharmaceutical, nutritional supplement, and functional food industries. We offer immediate-release, enteric-coated, and sustained-release solutions.
TiO₂-Free Capsules
Regulatory-ready opaque capsule shells without titanium dioxide (E171). Deliver uncompromising high-speed filling throughput.
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Anxine
info@anxine.com
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+86-137-5776-3288
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